回首頁 友善列印友善列印
葡萄及葡萄乾中毒
作者: 鄭美玉;賴政宏;鄭豐邦
中文病名: 葡萄及葡萄乾中毒
英文病名: Grape and raisin poisonings
疾病描述:

一、致病機制
2001年,美國防止虐待動物協會之動物毒物管制中心(The American Society for the Prevention of Cruelty to Animals Animal Poison Control Center, APCC)認為狗食用葡萄葡萄乾造成急性腎衰竭。目前引起腎衰竭的機制尚未確認,幾顆葡萄乾或幾磅葡萄皆有可能造成相同程度的毒性。文獻指出狗食用少量之葡萄葡萄乾(0.32~0.65 oz/kg),即可造成急性腎衰竭,可見近曲腎小管變性與壞死。

二、臨床症狀
在食用2~12小時後出現症狀,近八成患首先出現嘔吐的症狀,另外大部分患出現酒醉樣步態、行動困難顫抖運動失調;有半數患無尿寡尿的狀態,另外可能觀察到沉鬱、虛弱無力、腹痛及體溫過高。上述症狀最久可持續至五天。

預防控制方法:

1.將可能讓狗誤食之食品妥善收藏。
2.勿餵食人類食物,降低誤食機會。

相關圖片:

黃褐色結晶物沉積在患犬腎盂。

(Yoon SS, Byun JW, Kim MJ, Bae YC, Shin YK, Yoon S, Lee G, Song JY. Natural occurrence of grape poisoning in two dogs. J Vet Med Sci. 2010.提供)

黃褐色結晶物沉積在患犬腎盂。

(Yoon SS, Byun JW, Kim MJ, Bae YC, Shin YK, Yoon S, Lee G, Song JY. Natural occurrence of grape poisoning in two dogs. J Vet Med Sci. 2010.提供)

參考文獻:

1.Côté E, Khan SA. Intoxication versus acute, nontoxicologic illness: differentiating the two. In: Ettinger SJ, Feldman EC, eds. Textbook of veterinary internal medicine. 6th ed. Elsevier Saunders, Missouri, USA, 244, 2005.
2.Eubig PA, Brady MS, Gwaltney-Brant SM, Khan SA, Mazzaferro EM, Morrow CM. Acute renal failure in dogs after the ingestion of grapes or raisins: a retrospective evaluation of 43 dogs (1992-2002). J Vet Intern Med. 19:663-674, 2005.
3.Mazzaferro EM. Acute renal failure associated with raisin or grape ingestion in 4 dogs. J Vet Emerg Crit Care (San Antonio). 14:203-212, 2004.
4.Morrow CM, Valli VE, Volmer PA, Eubig PA. Canine renal pathology associated with grape or raisin ingestion: 10 cases. J Vet Diagn Invest. 17:223-231, 2005
5.Yoon SS, Byun JW, Kim MJ, Bae YC, Shin YK, Yoon S, Lee G, Song JY. Natural occurrence of grape poisoning in two dogs. J Vet Med Sci. 2010.

參考連結: